The maternal relationship between Louis Amelia Mildred Wilson and her son William Smith is confirmed by the direct inheritance path of autosomal DNA down to their DNA tested descendant TS.

The segmental (via DNA segment triangulation) and total DNA shared between TS and other confirmed descendants of Charles Edward Wilson/Sarah Jane Lee is consistent with the expected ranges for their respective relationships. Since TS descends from Charles Edward Wilson/Sarah Jane Lee through Louis Amelia Mildred Wilson and her son William Smith, the presence of significant shared DNA between TS and other known descendants of Charles Edward Wilson/Sarah Jane Lee validates the generational links along this maternal line.

This supports the conclusion that DNA was passed from MRCA couple Charles Edward Wilson/Sarah Jane Lee through Louis Amelia Mildred Wilson to William Smith, and ultimately to TS, confirming this direct ancestral connection through multiple generations.