The maternal relationship between Virginia Ann Van Meter and her son LS is confirmed by the direct inheritance path of autosomal DNA down to their DNA tested descendant LS.

The segmental (via DNA segment triangulation) and total DNA shared between LS and other confirmed descendants of John Harvey Uber, Jr./Chloe Voorhies is consistent with the expected ranges for their respective relationships. Since LS descends from John Harvey Uber, Jr./Chloe Voorhies through Virginia Ann Van Meter and her son LS, the presence of significant shared DNA between LS and other known descendants of John Harvey Uber, Jr./Chloe Voorhies validates the generational links along this maternal line.

This supports the conclusion that DNA was passed from MRCA couple John Harvey Uber, Jr./Chloe Voorhies through Virginia Ann Van Meter to LS, and ultimately to LS, confirming this direct ancestral connection through multiple generations.