The proposed relationship of Minnie Lera Reed as the mother of Robert Graham Sr. Wagner and William Isaac Wagner is supported by DNA evidence indicating shared ancestry within the family lines.

Specifically, DNA evidence confirms a distant cousin relationship between CCC (a descendant of the Robert Graham Sr. Wagner ancestral line) and WF (a descendant of the William Isaac Wagner ancestral line) with a shared segment of 45.11 cM across 3 HIR segments.

This match is consistent with their placement within these shared ancestral branches.